Corticotropin-Independent Macronodular Adrenal Hyperplasia

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Corticotropin-independent macronodular adrenal hyperplasia: a clinicopathologic correlation.

OBJECTIVES To investigate the clinical presentation, laboratory findings, and pathologic characteristics of patients with corticotropin (ACTH)-independent macronodular adrenal hyperplasia. DESIGN Retrospective review. SETTING Academic medical center. PATIENTS All patients with bilateral adrenocortical nodules associated with ACTH-independent hypercortisolism without clinicopathologic feat...

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ACTH-independent macronodular adrenal hyperplasia.

Adrenocorticotropic hormone- (ACTH-)independent macronodular adrenal hyperplasia (AIMAH) is an infrequent cause of Cushing's syndrome (CS). AIMAH presents as incidental radiological finding or with subclinical or overt CS, occasionally with secretion of mineralocorticoids or sex steroids. The pathophysiology of this entity is heterogeneous. The aberrant adrenal expression and function of one or...

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Adrenocorticotropic hormone independent macronodular adrenal hyperplasia.

1 of 2 DESCRIPTION Figure 1 is of a CT scan showing bilateral macronodular adrenal glands in a patient with adrenocorticotropic hormone-independent macronodular adrenal hyperplasia (AIMAH). AIMAH was fi rst described in 1964 1 . AIMAH is often discovered as a fortuitous radiological fi nding, as in our patient, or during investigation for endogenous hypercortisolism. AIMAH represents less than ...

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A Case of Adrenocorticotropin -Independent Macronodular Adrenal Hyperplasia (AIMAH)- A Case Report

The case-report is about a 47 year old woman with adrenocorticotropin-independent macronudular adrenal hyperplasia (AIMAH), with is a rare cause of endogenous Cushing’s syndrome. Urin free cortisol (UFC) and cortisol of 8AM were elevated along with the suppressed level of ACTH. Abdominal CT scan showed macronodules in both adrenals .The patient underwent left adrenalectomy and pathological dat...

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[ACTH-independent Cushing's syndrome secondary to macronodular adrenal hyperplasia].

incierto, lo que sı́ sabemos es que se produce una mejorı́a en la densidad mineral ósea y una disminución en el riesgo de fractura. El mecanismo implicado serı́a una restauración de la pulsatilidad de la PTH tras la cirugı́a, junto con un aumento de la mineralización y de la formación ósea. En esta mejorı́a de la paciente probablemente contribuyeron tanto la cirugı́a paratiroidea como el tratamiento ...

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ژورنال

عنوان ژورنال: Archives of Surgery

سال: 1998

ISSN: 0004-0010

DOI: 10.1001/archsurg.133.5.541